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Colloidal carbon stimulation of Kupffer cells triggers Nrf2 activation in the isolated perfused rat liver
Activation of transcription factor Nrf2 was investigated in the isolated perfused rat liver infused with 0.5 mg of colloidal carbon (CC)/ml for 5–15 min to stimulated Kupffer cell function. Infusion of CC enhanced liver ...
Thyroid hormone-induced cytosol-to-nuclear translocation of rat liver Nrf2 is dependent on Kupffer cell functioning
L-3,3 ,5-triiodothyronine (T3) administration upregulates nuclear factor-E2-related factor 2 (Nrf2) in rat liver, which is redoxsensitive transcription factor mediating cytoprotection. In this work, we studied the role of ...