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M2 macrophages do not fly into a “RAGE”
(2017)
Tumor-associated macrophages (TAMs) are key elements in orchestrating host responses inside tumor stroma. This population may undergo a polarized activation process, thus rendering a heterogeneous spectrum of phenotypes, ...
HMGB1 enhances the protumoral activities of M2 macrophages by a RAGE-dependent mechanism
(2016)
The monocyte-macrophage lineage shows a high degree of diversity and plasticity. Once they infiltrate tissues,they may acquire two main functional phenotypes, being known as the classically activated type 1 macrophages ...