After more than 50 years of repose, on September 19th, 2021, a volcanic eruption began at the Cumbre Vieja ridge on La Palma, Canary Islands. The combined effusive and explosive activity generated a > 12 km2 lava flow field with a new cone nearly 200 m higher than pre-eruptive topography and a vast tephra blanket. The immediate impact was locally devastating, destroying nearly 2000 buildings, blocking two main and numerous secondary roads, and inundating high-value agricultural land. The hybrid nature of the eruption and the observed variations in eruption intensity motivated a thorough investigation of bulk liquid viscosity at high temporal resolution. Collection of 82 lava samples was achieved at a near daily resolution over the course of the 85-day-long event (through the end of the eruption on December 13th, 2021). All the samples were remelted, and liquid viscosity was measured in a concentric cylinder viscometer from 1490 °C down to incipient crystallization temperatures. These data constitute the highest temporal resolution viscosity dataset obtained for an eruptive sequence to date. A tripartite viscosity pattern is identified at isothermal conditions: 1) during the fissure opening and establishing stage (days 1–20) a linear decrease in melt viscosity occurred; 2) during most of the eruption duration (days 21–70) viscosity was constant and 3) from day 70 until the end of the eruption viscosity increased again. We interpret this pattern as magma being extracted from different parts of the plumbing system over the course of the eruption. Accordingly, we show that viscosity time series can help shed light on some of the complexities of volcanic plumbing system. Additionally, the presented results highlight the monitoring potential of the viscosity assessment approach, specifically in regard to forecasting eruption behavior using direct information about magma mobility and detecting changes in magmatic plumbing system dynamics.