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Non-alcoholic fatty liver and periodontal disease in the adult population: overview of systematic reviews
| dc.contributor.author | Fuentes-Barría, Héctor | |
| dc.contributor.author | Klahn-Acuña, Blanca | |
| dc.contributor.author | Sepúlveda-Toro, Denisse | |
| dc.contributor.author | Galaz-Cáceres, Najarett | |
| dc.contributor.author | Aguilera-Eguía, Raúl | |
| dc.contributor.author | Alarcón-Rivera, Miguel | |
| dc.date.accessioned | 2025-03-26T12:43:40Z | |
| dc.date.available | 2025-03-26T12:43:40Z | |
| dc.date.issued | 2024 | |
| dc.identifier.uri | http://repositorio.ucm.cl/handle/ucm/5883 | |
| dc.description.abstract | Introduction: Periodontal disease is a chronic inflammatory condition affecting the periodontal supporting tissues. In addition to dental loss, it has been associated with various metabolic disorders, including obesity, diabetes, dyslipidemia, and non-alcoholic fatty liver disease (NAFLD). This study aimed to analyze the effects of periodontal disease on the prevention and treatment of NAFLD in the adult population. Method: An electronic search of systematic reviews published between 2019 and 2024 was conducted in the Medline, Scopus, and Web of Science databases, as well as in the Epistemonikos meta-search engine. The search strategy was "Non-alcoholic Fatty Liver Disease AND Periodontitis". A total of 47 articles were identified, of which three systematic reviews with meta-analyses were analyzed. Results: The results indicated a potential association between periodontal disease and NAFLD, with an odds ratio (OR) of 1.48 (95% CI: 1.15 to 1.89; I² = 92%) and 1.91 (95% CI: 1.21 to 3.02; I² = 95%). However, this link has not been definitively proven, as heterogeneity decreases and the number of patients increases, resulting in an OR of 1.04 (95% CI: 0.97 to 1.12; I² = 58%). Conclusion: It is suggested that systemic inflammation and pro-inflammatory markers may play a significant role in the pathophysiology of both conditions. Nonetheless, further studies are needed to clarify this relationship and explore the common metabolic parameters. | es_CL |
| dc.language.iso | en | es_CL |
| dc.rights | Atribución-NoComercial-SinDerivadas 3.0 Chile | * |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | * |
| dc.source | Salud, Ciencia y Tecnología, 4, 1016 | es_CL |
| dc.subject | Non-alcoholic Fatty Liver Disease | es_CL |
| dc.subject | Periodontitis | es_CL |
| dc.subject | Periodontal | es_CL |
| dc.subject | Diseases | es_CL |
| dc.subject | Porphyromonas gingivalis | es_CL |
| dc.subject | Quality of Life | es_CL |
| dc.title | Non-alcoholic fatty liver and periodontal disease in the adult population: overview of systematic reviews | es_CL |
| dc.type | Article | es_CL |
| dc.ucm.facultad | Facultad de Medicina | es_CL |
| dc.ucm.indexacion | Scopus | es_CL |
| dc.ucm.uri | sct.ageditor.ar/index.php/sct/article/view/1016 | es_CL |
| dc.ucm.doi | doi.org/10.56294/saludcyt2024.1016 | es_CL |
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