This retrospective study compared oxygenation, hypopnea episodes, micro-arousals, and periodic limb movements in individuals with sleep bruxism and a control group. A total of 129 polysomnography records from 2011 to 2019 were analyzed (54 with SB, 74 controls). Subjects with sleep bruxism were classified according to Lavigne et al. (≥25 events/hour). Variables included sex, age, micro-arousals, oxygenation, hypopnea episodes, and periodic limb movements. The Mann-Whitney U test was used for comparisons. Subjects with sleep bruxism had a higher average number of micro-arousals: NMOR (SB: 29.5 vs. Control: 24.3) and MOR (sleep bruxism: 18.5 vs. Control: 13.2). Respiratory events with arousals were twice as frequent (sleep bruxism: 3.07 vs. Control: 1.69), and hypopnea episodes were more frequent and lasted longer in sleep bruxism (34.09 episodes, 11.5 sec) compared to controls (24.38 episodes, 7.4 sec). Oxygenation was lower in controls but remained within normal limits: NMOR (SB: 92.6 vs. Control: 89) and MOR (sleep bruxism: 92.9 vs. Control: 88). periodic limb movements frequency was also higher in sleep bruxism (sleep bruxism: 72.4 vs. Control: 65.7), though differences were not statistically significant (p > 0.05). In conclusion, sleep bruxism was associated with more frequent micro-arousals, hypopnea episodes, and periodic limb movements compared to controls, while oxygenation levels were lower in the control group.