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Mostrando publicaciones 1-20 de 21
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Are people with metabolically healthy obesity really healthy? A prospective cohort study of 381,363 UK Biobank participants
Zhou, Ziyi; Macpherson, John; Gray, S.R.; Gill, Jason M.R.; Welsh, Paul; Celis-Morales, Carlos; Sattar, Naveed; Pell, J.P.; Ho, Frederick (2021)Aims/hypothesis: People with obesity and a normal metabolic profile are sometimes referred to as having ‘metabolically healthy obesity’ (MHO). However, whether this group of individuals are actually ‘healthy’ is uncertain. ...
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Association between device-measured physical activity and incident heart failure: a prospective cohort study of 94 739 uk biobank participants
Ho, Frederick; Zhou, Ziyi; Petermann-Rocha, Fanny; Para-Soto, Solange; Boonpor, Jirapitcha; Welsh, Paul; Gill, Jason M.R.; Gray, S.R.; Sattar, Naveed; Pell, J.P.; Celis-Morales, Carlos (2022)Background: Studies of objectively measured physical activity (PA) have investigated acute cardiovascular outcomes but not heart failure (HF), an emerging chronic condition. This study aimed to investigate the dose-response ...
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Association of sarcopenia with incident osteoporosis: a prospective study of 168,682 UK biobank participants
Petermann-Rocha, Fanny; Ferguson, Lyn D.; Gray, S.R.; Rodríguez-Gómez, Irene; Sattar, Naveed; Siebert, Stefan; Ho, Frederick; Pell, J.P.; Celis-Morales, Carlos (2021)Background: Sarcopenia often co-occurs with osteoporosis in cross-sectional studies. However, this association has rarely been studied in prospective studies. This study aimed to investigate the association between sarcopenia ...
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Associations and predictive performance of 11 anthropometric measures with incident type 2 diabetes: a prospective cohort study from the UK Biobank
Boonpor, Jirapitcha; Parra‑Soto, Solange; Talebi, Atefeh; Zhou, Ziyi; Carrasco-Marin, Fernanda; Petermann-Rocha, Fanny; Welsh, Paul; Pell, J.P.; Sattar, Naveed; Gill, Jason M.R.; Gray, S.R.; Celis-Morales, Carlos; Ho, Frederick (2023)Objective The study aim was to investigate associations of 11 anthropometric measures with incident type 2 diabetes and compare their predictive performance. Methods This prospective cohort study included 161,127 White ...
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Associations between diet and handgrip strength: a cross-sectional study from UK biobank
Gedmantaite, A.; Celis-Morales, Carlos; Ho, Frederick; Pell, J.P.; Ratkevicius, A.; Gray, S.R. (2020)The aim of the current study was to investigate the association between diet and handgrip strength. The current study included 68,002 participants (age 63.8 ± 2.7 years, 50.3% women, 49.7% men) from UK Biobank. Diet and ...
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Associations between grip strength and incident type 2 diabetes: findings from the UK Biobank prospective cohort study
Boonpor, Jirapitcha; Parra, Solange; Petermann-Rocha, Fanny; Ferrari, Gerson Luis de Moraes; Welsh, Paul; Pell, J.P.; Sattar, Naveed; Gill, Jason M.R.; Ho, Frederick; Gray, S.R.; Celis-Morales, Carlos (2021)Introduction: Grip strength has been associated with chronic diseases and mortality. However, current evidence of the association between grip strength and incident type 2 diabetes mellitus (T2DM) is controversial. The aim ...
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Associations between physical frailty and dementia incidence: a prospective study from UK Biobank
Petermann-Rocha, Fanny; Lyall, Donald; Gray, S.R.; Esteban-Cornejo, Irene; Quinn, Terence J.; Ho, Frederick; Pell, J.P.; Celis-Morales, Carlos (2020)Background: Dementia is associated with a high burden of dependency and disability. Physical frailty (hereafter referred to as frailty) is a multisystem dysregulation that has been identified as a risk factor for dementia. ...
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Associations of fat and carbohydrate intake with cardiovascular disease and mortality: prospective cohort study of UK Biobank participants
Ho, Frederick; Gray, S.R.; Welsh, Paul; Petermann-Rocha, Fanny; Foster, Hamish M. E.; Waddell, Heather; Anderson, Jana J.; Lyall, Donald; Sattar, Naveed; Gill, Jason M.R.; Mathers, John; Pell, J.P.; Celis-Morales, Carlos (2020)Objective: To investigate the association of macronutrient intake with all cause mortality and cardiovascular disease (CVD), and the implications for dietary advice. Design: Prospective population based study. Setting: ...
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Biomarkers profile of people with sarcopenia: a cross-sectional analysis from UK Biobank
Petermann-Rocha, Fanny; Gray, S.R.; Pell, J.P.; Celis-Morales, Carlos; Ho, Frederick (2020)Objective: This study aimed to characterize the biomarker profile of sarcopenic vs nonsarcopenic men and women, using the current European Working Group on Sarcopenia in Older People (EWGSOP2) definition in the UK Biobank ...
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Child maltreatment and cardiovascular disease: quantifying mediation pathways using UK biobank
Ho, Frederick; Celis-Morales, Carlos; Gray, S.R.; Petermann-Rocha, Fanny; Lyall, Donald; Mackay, Daniel; Sattar, Naveed; Minnis, Helen; Pell, J.P. (2020)Background: Child maltreatment is associated with cardiovascular disease (CVD), but mediation pathways have not been fully elucidated. The aim of the current study was to determine and quantify the underlying pathways ...
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Combined association of general and central obesity with incidence and mortality of cancers in 22 sites
Parra, Solange; Petermann-Rocha, Fanny; Boonpor, Jirapitcha; Gray, S.R.; Pell, J.P.; Celis-Morales, Carlos; Ho, Frederick (2021)Background: Body mass index (BMI) and waist circumference (WC) are measures of general and central obesity, respectively, and both have been shown to be associated with cancer. However, there is insufficient evidence of ...
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Comparison of two different frailty measurements and risk of hospitalisation or death from COVID-19: findings from UK Biobank
Petermann-Rocha, Fanny; Hanlon, Peter; Gray, S.R.; Welsh, Paul; Gill, Jason M.R.; Foster, Hamish M. E.; Katikireddi, Vittal S.; Lyall, Donald; Mackay, Daniel; O’Donnell, Catherine A.; Sattar, Naveed; Nicholl, Barbara I.; Pell, J.P.; Jani, Bhautesh D.; Ho, Frederick; Mair, Frances S.; Celis-Morales, Carlos (2020)Background. Frailty has been associated with worse prognosis following COVID-19 infection. While several studies have reported the association between frailty and COVID-19 mortality or length of hospital stay, there have ...
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Device-measured physical activity and incident afective disorders
Ho, Frederick; Petermann-Rocha, Fanny; Parra‑Soto, Solange; Boonpor, Jirapitcha; Gill, Jason M.R.; Gray, S.R.; Pell, J.P.; Celis-Morales, Carlos (2022)Background: Studies on physical activity (PA) and mental health are largely limited to self-reported PA. This study aims to use prospective cohort data to investigate the association between device-measured PA and ...
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Does the association between physical capability and mortality differ by deprivation? Findings from the UK Biobank population-based cohort study
Rey-López, Juan P.; Frederick, K. W.; Foster, Hamish M. E.; Petermann-Rocha, Fanny; Sattar, Naveed; Pell, J.P.; Gill, Jason M.R.; Gray, S.R.; Celis-Morales, Carlos (2020)Background: To investigate whether the excess risk of adverse health outcomes associated with a lower physical capability in adulthood differs by deprivation levels. Methods: 279,030 participants from the UK Biobank were ...
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Dose–response relationship between device-measured physical activity and incident type 2 diabetes: findings from the UK Biobank prospective cohort study
Boonpor, Jirapitcha; Parra‑Soto, Solange; Petermann-Rocha, Fanny; Lynskey, Nathan; Cabanas-Sánchez, Verónica; Sattar, Naveed; Gill, Jason M.R.; Welsh, Paul; Pell, J.P.; Gray, S.R.; Ho, Frederick; Celis-Morales, Carlos (2023)Background Most studies investigating the association between physical activity (PA) and the risk of type 2 diabetes are derived from self-reported questionnaires, with limited evidence using device-based measurements. ...
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Nonlinear associations between cumulative dietary risk factors and cardiovascular diseases, cancer, and all-cause mortality: a prospective cohort study from UK Biobank
Petermann-Rocha, Fanny; Ho, Frederick; Foster, Hamish M. E.; Boopor, Jirapitcha; Parra, Solange; Gray, S.R.; Mathers, John; Celis-Morales, Carlos; Pell, J.P. (2021)Objective: To develop a score from cumulative dietary risk factors and examine its nonlinear associations with cardiovascular disease (CVD) and cancer incidence and mortality, as well as all-cause mortality. Patients and ...
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Physical capability markers used to define sarcopenia and their association with cardiovascular and respiratory outcomes and all-cause mortality: a prospective study from UK biobank
Petermann-Rocha, Fanny; Ho, Frederick; Welsh, Paul; Mackay, Daniel; Brown, Rosemary E.; Gill, Jason M.R.; Sattar, Naveed; Gray, S.R.; Pell, J.P.; Celis-Morales, Carlos (2020)Introduction: It is unclear what combinations of physical capability markers used to define sarcopenia have the strongest associations with health outcomes. Aim: To compare the associations between different combinations ...
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Sarcopenic obesity and its association with respiratory disease incidence and mortality – Authors’ reply
Petermann-Rocha, Fanny; Yang, Shuai; Gray, S.R.; Pell, J.P.; Celis-Morales, Carlos; Ho, Frederick (2021) -
The joint association of sarcopenia and frailty with incidence and mortality health outcomes: A prospective study
Petermann-Rocha, Fanny; Gray, S.R.; Pell, J.P.; Ho, Frederick; Celis-Morales, Carlos (2021)Background: Sarcopenia and frailty are strongly associated with disease incidence and mortality. However, there is limited evidence regarding their joint association with health outcomes. This study aimed to investigate ...
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Understanding how much TV is too much: a nonlinear analysis of the association between television viewing time and adverse health outcomes
Foster, Hamish M. E.; Ho, Frederick; Sattar, Naveed; Welsh, Paul; Pell, J.P.; Gill, Jason M.R.; Gray, S.R.; Celis-Morales, Carlos (2020)Objective: To inform potential guideline development, we investigated nonlinear associations between television viewing time (TV time) and adverse health outcomes. Methods: From 2006 to 2010, 490,966 UK Biobank participants, ...