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Physical capability markers used to define sarcopenia and their association with cardiovascular and respiratory outcomes and all-cause mortality: a prospective study from UK biobank
(2020)
Introduction: It is unclear what combinations of physical capability markers used to define sarcopenia have the strongest associations with health outcomes. Aim: To compare the associations between different combinations ...
Child maltreatment and cardiovascular disease: quantifying mediation pathways using UK biobank
(2020)
Background: Child maltreatment is associated with cardiovascular disease (CVD), but mediation pathways have not been fully elucidated. The aim of the current study was to determine and quantify the underlying pathways ...
Alzheimer's disease susceptibility gene Apolipoprotein E (APOE) and blood biomarkers in UK Biobank (N = 395,769)
(2020)
Background: Alzheimer's disease (AD) is a neurodegenerative condition where the underlying etiology is still unclear. Investigating the potential influence of apolipoprotein E (APOE), a major genetic risk factor, on common ...
Vegetarians, fish, poultry, and meat-eaters: Who has higher risk of cardiovascular disease incidence and mortality? A prospective study from UK Biobank
(2021)
Aims: To compare the incidence and mortality risk for cardiovascular diseases (CVD) [CVD and also ischaemic heart disease (IHD), myocardial infarction (MI), stroke, and heart failure (HF)] among people with different types ...
Comparison of two different frailty measurements and risk of hospitalisation or death from COVID-19: findings from UK Biobank
(2020)
Background. Frailty has been associated with worse prognosis following COVID-19 infection. While several studies have reported the association between frailty and COVID-19 mortality or length of hospital stay, there have ...
An opportunity for prevention: associations between the life's essential 8 score and cardiovascular incidence using prospective data from uk biobank
(2023)
To investigate the association between the Life's Essential 8 (LE8) score and the incidence of four cardiovascular outcomes (ischemic heart disease, myocardial infarction, stroke, and heart failure [HF]) – separately and ...
Association of sarcopenia with incident osteoporosis: a prospective study of 168,682 UK biobank participants
(2021)
Background: Sarcopenia often co-occurs with osteoporosis in cross-sectional studies. However, this association has rarely been studied in prospective studies. This study aimed to investigate the association between sarcopenia ...
Are people with metabolically healthy obesity really healthy? A prospective cohort study of 381,363 UK Biobank participants
(2021)
Aims/hypothesis: People with obesity and a normal metabolic profile are sometimes referred to as having ‘metabolically healthy obesity’ (MHO). However, whether this group of individuals are actually ‘healthy’ is uncertain. ...
Associations between grip strength and incident type 2 diabetes: findings from the UK Biobank prospective cohort study
(2021)
Introduction: Grip strength has been associated with chronic diseases and mortality. However, current evidence of the association between grip strength and incident type 2 diabetes mellitus (T2DM) is controversial. The aim ...
Association between device-measured physical activity and incident heart failure: a prospective cohort study of 94 739 uk biobank participants
(2022)
Background:
Studies of objectively measured physical activity (PA) have investigated acute cardiovascular outcomes but not heart failure (HF), an emerging chronic condition. This study aimed to investigate the dose-response ...