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dc.contributor.authorPetermann-Rocha, Fanny
dc.contributor.authorCarrasco-Marin, Fernanda
dc.contributor.authorBoonpor, Jirapitcha
dc.contributor.authorParra‑Soto, Solange
dc.contributor.authorShannon, Oliver
dc.contributor.authorMalcomson, Fiona C.
dc.contributor.authorPhillips, Nathan
dc.contributor.authorJain, Mahek
dc.contributor.authorDeo, Salil
dc.contributor.authorLivingstone, Katherine M.
dc.contributor.authorDingle, Sara E.
dc.contributor.authorMathers, John
dc.contributor.authorForrest, Ewan
dc.contributor.authorHo, Frederick
dc.contributor.authorPell, Jill P.
dc.contributor.authorCelis-Morales, Carlos
dc.date.accessioned2025-03-26T12:33:02Z
dc.date.available2025-03-26T12:33:02Z
dc.date.issued2024
dc.identifier.urihttp://repositorio.ucm.cl/handle/ucm/5870
dc.description.abstractAim This study aimed to contrast the associations of five common diet scores with severe non-alcoholic fatty liver disease (NAFLD) incidence. Materials and Methods In total, 162 999 UK Biobank participants were included in this prospective population-based study. Five international diet scores were included: the 14-Item Mediterranean Diet Adherence Screener (MEDAS-14), the Recommended Food Score (RFS), the Healthy Diet Indicator (HDI), the Mediterranean Diet Score and the Mediterranean-DASH Intervention for Neurodegenerative Delay score. As each score has different measurements and scales, all scores were standardized and categorized into quartiles. Cox proportional hazard models adjusted for confounder factors investigated associations between the standardized quartiles and severe NAFLD incidence. Results Over a median follow-up of 10.2 years, 1370 participants were diagnosed with severe NAFLD. When the analyses were fully adjusted, participants in quartile 4 using the MEDAS-14 and RFS scores, as well as those in quartiles 2 and 3 using the HDI score, had a significantly lower risk of severe incident NAFLD compared with those in quartile 1. The lowest risk was observed in quartile 4 for the MEDAS-14 score [hazard ratio (HR): 0.76 (95% confidence interval (CI): 0.62-0.94)] and the RFS score [HR: 0.82 (95% CI: 0.69-0.96)] and as well as in quartile 2 in the HDI score [HR: 0.80 (95% CI: 0.70-0.91)]. Conclusion MEDAS-14, RFS and HDI scores were the strongest diet score predictors of severe NAFLD. A healthy diet might protect against NAFLD development irrespective of the specific approach used to assess diet. However, following these score recommendations could represent optimal dietary approaches to mitigate NAFLD risk.es_CL
dc.language.isoenes_CL
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 Chile*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/*
dc.sourceDiabetes, Obesity and Metabolism, 26(3), 860-870es_CL
dc.subjectDietes_CL
dc.subjectNon-alcoholic fatty liver diseasees_CL
dc.subjectIncidencees_CL
dc.titleAssociation of five diet scores with severe NAFLD incidence: a prospective study from UK Biobankes_CL
dc.typeArticlees_CL
dc.ucm.indexacionScopuses_CL
dc.ucm.indexacionIsies_CL
dc.ucm.uridom-pubs.pericles-prod.literatumonline.com/doi/10.1111/dom.15378es_CL
dc.ucm.doidoi.org/10.1111/dom.15378es_CL


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Atribución-NoComercial-SinDerivadas 3.0 Chile
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