Producción Académica: Envíos recientes
Mostrando publicaciones 1-20 de 3852
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Computational estimation of residence time on Roniciclib and its derivatives against CDK2: extending the use of classical and enhanced molecular dynamics simulations
(2025)Residence time is a crucial parameter for assessing the functional efficacy of drugs, quantifying the duration of a drug’s binding to its target protein. It is directly related to therapeutic effects and the dosing regimen. ...
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La enajenación mental en Chile: institucionalidad en el periodo de 1852–1928
(2025)La salud mental en Chile, y la concepción sobre esta, fue testigo de una serie de transformaciones durante el siglo XIX e inicios del siglo XX, producto de hallazgos y reformas que se implementaron en otros continentes y ...
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Asociación entre el fitness cardiorrespiratorio y el riesgo de mortalidad en la población chilena
(2025)FUNDAMENTOS // El fitness cardiorrespiratorio disminuye el riesgo de enfermedades cardiometabólicas, de cáncer y la mortalidad. El objetivo de este trabajo fue evaluar la relación entre el fitness cardiorrespiratorio ...
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Effectiveness of occupational therapy interventions on activities of daily living, cognitive function, and physical function in middle-aged and older people with chronic stroke: a systematic review with meta-analysis
(2025)Background: Occupational therapy (OT) interventions on activities of daily living (ADL), cognitive functions, and physical function in middle-aged and older people with chronic stroke. Methods: A systematic review search ...
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A Cross-cultural exploration of problematic Internet use, pathological personality traits, defense mechanisms, coping strategies, and self-esteem in 14 countries
(2025)Objectives The primary objective of this study was to compare the estimates of Problematic Internet Use (PIU) from 14 countries around the world, considering gender. The second objective was to explore the relationships ...
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Xbox Kinect Sports effects on cognition status and physical performance in physically inactive older females: a randomized controlled trial
(2025)Background/Objectives: This study aimed to compare the effects of Xbox Kinect Sports (XKS) relative to an inactive control group (CG) on cognitive status and physical performance in physically inactive older females. ...
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Comparación de la memoria de trabajo y la velocidad de reacción de miembros superiores entre jóvenes tenismesistas y estudiantes universitarios
(2025)El tener una adecuada velocidad de reacción (VR), ayuda a preparar el cerebro para afrontar los desafíos de forma rápida y eficaz. El objetivo fue comparar la memoria de trabajo (MT) y la VR de miembros superiores, entre ...
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Rational design, synthesis, and evaluation of novel polypharmacological compounds targeting NaV1.5, KV1.5, and K2P channels for atrial fibrillation
(2025)Atrial fibrillation (AF) involves electrical remodeling of the atria, with ion channels such as NaV1.5, KV1.5, and TASK-1 playing crucial roles. This study investigates acetamide-based compounds designed as multi-target ...
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Effectiveness of combined cognitive stimulation and physical activity interventions on activities of daily living, cognitive function, and physical function in older people with mild cognitive impairment: a systematic review with meta-analysis
(2025)Background/Objectives: This systematic review with meta-analysis aimed to evaluate and synthesize scientific evidence about the combined cognitive stimulation and physical activity interventions on Activities of Daily ...
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The TRPV3 channel is a mediator of zinc influx and homeostasis in murine oocytes
(2025)Zinc (Zn2+) homeostasis is essential for gametogenesis and reproduction, and its deficiency causes infertility. Oocytes contain higher Zn2+ levels than somatic cells, and Zn2+ concentrations in oocytes are far higher than ...
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Multiple local and global bifurcations and their role in quorum sensing dynamics
(2025)Quorum sensing governs bacterial communication, playing a crucial role in regulating population behaviour. We propose a mathematical model that uncovers chaotic dynamics within quorum sensing networks, highlighting challenges ...
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Transformative mixed methods evaluation of a recovery-based intervention for adult suicide reattempters in Chile: study protocol
; Méndez-Bustos, Pablo
(2025)
Suicide is a serious social and public health problem worldwide. Chile has experienced a dangerously high suicide rate for some time and, despite intervention efforts, there is a gap, especially in cases of recidivism. ...
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Gyneco-obstetric violence and its impact on the mental health of women with disabilities: a case study in Chile
(2025)Although gyneco-obstetric violence (GOV) addresses the violation of sexual and reproductive rights, it is crucial to problematize its subjective aspects and effects on the mental health of women with disabilities, especially ...
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Conical waveguide design for propagating light to a single fiber and its indoor characterization methodology
(2025)This study introduces a novel optical setup and methodology to increase the effective area of a multimode optical fiber (MMF) using a low-cost, 3D-printed conical waveguide (CW). Designed to simplify solar collection systems ...
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Workload, job, and family satisfaction in dual-earning parents with adolescents: the mediating role of work-to-family conflict
(2025)Introduction: The study examined the direct and indirect effects of parents’ workload, work-to-family conflict (WtoFC), job satisfaction, and family satisfaction among dual-earning parents and their adolescent children. Methods: ...
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Impact of methyl Jasmonate on blueberry ripening fruits: assessment of cell wall thermal stability, nutritional parameters and antioxidant enzymatic activity
(2025)Introduction: The blueberry (Vaccinium spp.), recognized as one of the most significant horticultural crops globally, is valued for its rich bioactive compounds. In this study, we examine the effects of methyl jasmonate ...
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The constitutional protection of intangible assets in Chile and the problem of their determination in contracts between private parties
(2025)Sin perjuicio de todas las dudas que rondan a la “propietarización de los derechos”, en Chile parece existir un consenso básico: los bienes de naturaleza incorporal pueden ser garantizados constitucionalmente mediante el ...
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Epistemological beliefs in mathematics teacher educators: an exploratory study in Chile
(2025)In Chile, mathematics results are insufficient at the school level. To address this problem, the need to rethink teaching has been raised. Evidence indicates that epistemological beliefs are at the basis of pedagogical ...
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Aliens vs. paper wasps: new records of Darwin wasps parasitizing social wasps in Brazil
(2025)This study reports new associations between Ichneumonidae and social wasps, contributing to the understanding of the ecological relationships between species and expanding current knowledge of their geographic distribution. ...